Welcome to the BIDMC Mass Spectrometry Core

'Specializing in a targeted proteomics approach towards cellular signaling

ABOUT US: The mass spectrometry and proteomics core at Beth Israel Deaconess Medical Center was established in 2004 and continues to grow rapidly. We provide excellent proteomics services with low prices and fast turnaround times. We have cutting edge equipment operated at optimal sensitivity and work with world class researchers. We also mainatin a very active internal cancer proteomics research program with collaborative efforts. Our expertise is in identifying and quantifying protein modifications and dynamic protein-protein interactions in addition to metabolomics analyses. We look forward to helping you and progressing your research to the next level.

Post-Doctoral Researcher needed, click here for the job description.

Proteomics Services Provided

  • Protein Complex Identification
    (protein complexes, protein-protein interactions)
  • Identification of Post-Translational Modifications
    (phosphorylation, acetylation, ubiquitination, etc.)
  • Relative Quantification
    (Label-free quantification, SILAC, ISIL, etc.)
    • Protein complex stoichiometry
    • Quantification of phosphorylation sites
    • PPI networks 
  • Metabolomics Profiling  

 Instrumentation

  • Thermo Scientific LTQ Orbitrap XL-ETD
    (ultra high resolution and mass accuracy, HCD collision cell, ETD fragmentation for labile modifications)
  • Thermo Scientific LTQ 2D linear ion trap
    (very fast and very sensitive, great for protein ID)
  • Applied Biosystems/MDS Sciex 5500 QTRAP triple quadrupole
    (targeted label-free quantitation and Metabolomics profiling)
  • Proxeon EASY-nLC (2)
    (nanoliter flow rates, very reproducible and robust)
  • Shimadzu Prominence UFLC
  • Michrom Bioresources Paradigm 2D-HPLC

    ThermoScientific LTQ Orbitrap XL-ETD

                  

    Proxeon EASY-nLC

     

       

 

 

 

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