Welcome to the BIDMC Mass Spectrometry Core

'Specializing in a targeted proteomics & metabolomics approach towards cellular signaling'

ABOUT USThe mass spectrometry, metabolomics and proteomics core at Beth Israel Deaconess Medical Center was established in 2004 led by Dr. John Asara and continues to grow rapidly. We provide excellent proteomics and metabolomics services with low prices and fast turnaround times. We have cutting edge equipment operated at optimal sensitivity and work with world class researchers. We also mainatin an active internal cancer proteomics research program with collaborative efforts. Our expertise is in identifying and quantifying protein modifications and dynamic protein-protein interactions in addition to metabolomics profiling analyses. We look forward to helping you and progressing your research to the next level.

NEWS: 

  • We have lowered our prices for external academic users and corporate users!!
  • We just lowered our prices for large orders with more than 10 samples (proteomics only)

Proteomics & Metabolomics Services

  • Protein Complex Identification
    (protein complexes, protein-protein interactions, single protein ID)
  • Identification of Post-Translational Modifications
    (phosphorylation, acetylation, ubiquitination, etc.)
  • Relative Protein Quantification
    (Label-free quantification, SILAC, Avg. TIC, iTRAQ)
    • Protein complex stoichiometry
    • Quantification of phosphorylation sites
    • PPI networks 
  • Quantitative Metabolomics Profiling  
    (endogenous polar metabolites from any cell or tissue source) 
    • Steady-state profiling
    • C13/N15 metabolic flux analysis

Instrumentation

  • Thermo Scientific LTQ Orbitrap XL-ETD
    (ultra high resolution and mass accuracy, HCD collision cell, ETD fragmentation for labile modifications)
  • Thermo Scientific LTQ 2D linear ion trap
    (very fast and very sensitive, great for protein ID)
  • Applied Biosystems/MDS Sciex 5500 QTRAP triple quadrupole
    (targeted label-free quantitation and Metabolomics profiling)
  • Proxeon EASY-nLC (2)
    (nanoliter flow rates, very reproducible and robust)
  • Shimadzu Prominence UFLC
  • Michrom Bioresources Paradigm 2D-HPLC

    Coming Soon: ThermoScientific Orbitrap Velos Pro


    ThermoScientific LTQ Orbitrap XL-ETD

                  
  • Thermo (Proxeon) EASY-nLCII


    AB/SCIEX 5500 QTRAP

 

     

 

 

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