Welcome to the BIDMC Mass Spectrometry Core
'Specializing in a targeted proteomics & metabolomics approach towards cellular signaling'
Proteomics on Dinosaurs or "Fossilomics":
Study #1: Protein from a 68 million year old T. rex fossil sequenced at BIDMC Mass Spec Core
-Featured in the New York Times, Washington Post, Boston Globe, Newsweek, Discover Magazine, MSNBC, etc.
Study #2: Amino acid sequence from collagen used to perform rigorous phylogenetics analysis on T. rex and mastodon fossils
Study #3: Collagen from an 80 million year old Hadrosaur Brachylophosaurus canadensis sequenced by Orbitrap mass spectrometry
Proteomics/Metabolomics of Cancer Signaling:
Study: Using tandem mass spectrometry to choose appropriate kinase inhibitor drugs in cancers: A personalized medicine strategy based on protein-protein interactions
Recent Poster: A mass spectrometry platform to quantitatively profile cancer cell metabolism from cell lines, fluids and tissues
Study: Metabolomics from Formalin Fixed Paraffin Embedded (FFPE) Tumor Tissue
Study: A simple method for quantifying proteins between experimental conditions based on MS/MS TIC
Study: A label-free method for quantification of protein phosphorylation sites based on MS/MS TIC values from targeted runs
Study: Detection of a phosphohistidine residue by LC/MS/MS using HCD that is critical to an alternative glycolytic pathway
Coming soon:
For latest manuscripts, click below (will be updated soon):
