Proteomics on Dinosaurs or "Fossilomics":

Study #1: Protein from a 68 million year old T. rex fossil sequenced at BIDMC Mass Spec Core

-Featured in the New York Times, Washington Post, Boston Globe,  Newsweek, Discover Magazine, MSNBC, etc.

Study #2: Amino acid sequence from collagen used to perform rigorous phylogenetics analysis on T. rex and mastodon fossils

Study #3: Collagen from an 80 million year old Hadrosaur Brachylophosaurus canadensis sequenced by Orbitrap mass spectrometry

Proteomics/Metabolomics of Cancer Signaling:

Study: Using tandem mass spectrometry to choose appropriate kinase inhibitor drugs in cancers: A personalized medicine strategy based on protein-protein interactions

Recent Poster:  A mass spectrometry platform to quantitatively profile cancer cell metabolism from cell lines, fluids and tissues

Study: Metabolomics from Formalin Fixed Paraffin Embedded (FFPE) Tumor Tissue

Study: A simple method for quantifying proteins between experimental conditions based on MS/MS TIC

Study: A label-free method for quantification of protein phosphorylation sites based on MS/MS TIC values from targeted runs

Study:  Detection of a phosphohistidine residue by LC/MS/MS using HCD that is critical to an alternative glycolytic pathway

Coming soon:

• Comparing fly and human cancer PPI datasets
•  A novel protein interaction with PI3K
• Using proteomics strategies to find the upstream RTK activating pathways in cancers
  

                                                  
        For latest manuscripts, click below (will be updated soon):